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Cold Email Cadence: Timing and Frequency Guide

  • Silvio Bonomi
  • Mar 28
  • 6 min read

Updated: Apr 1

  • Timing matters: Send emails during business hours, ideally Tuesday–Thursday, between 10:00–11:00 AM or 2:00–3:00 PM in the recipient's time zone.
  • Follow-up smartly: Space follow-ups over 2–3 weeks. Example:
    • Day 1: Initial email
    • Day 4: Follow-up # 1
    • Day 8: Follow-up # 2
    • Day 14: Final email
  • Personalize every email: Mention their role, company, or industry challenges to stand out.
  • Use multiple channels: Combine email with LinkedIn outreach for better engagement.

Want to refine your strategy? Track metrics like open rate (15–25%), reply rate (5–15%), and bounce rate (under 5%). Tools can help you automate, test, and analyze your campaigns for continuous improvement.

Pro Tip: Keep emails short, clear, and focused on value. Lead with a strong subject line and a clear call-to-action.


Optimal Number Of Steps In a Cold Email Sequence ...


Core Elements of Cold Email Cadence

Understanding and applying the key elements of cold email cadence can improve your outreach success.


Email Timing Basics

Timing plays a crucial role in the effectiveness of your email cadence:

  • Business Hours: Schedule emails during standard working hours (9 AM–5 PM) in your recipient's time zone.
  • Work Week Patterns: Engagement rates tend to be higher between Tuesday and Thursday.
  • Industry-Specific Timing: Match your email timing to the recipient's industry habits. For instance, retail executives often check emails early in the morning before store hours.

Research from Artemis Leads (https://artemisleads.com) suggests that personalizing send times can improve engagement. Once you've nailed the timing, focus on spacing your follow-ups effectively.


Email Spacing and Follow-ups

Email Stage

Timing

Purpose

Initial Email

Day 1

Introduce yourself and present your value.

First Follow-up

Day 3-4

Add more context or information.

Second Follow-up

Day 7-8

Share a case study or a useful insight.

Final Message

Day 14

Wrap up with a clear call-to-action.

Spacing your emails thoughtfully keeps you on the recipient's radar without overwhelming them.


Message Customization

Personalized messages make your outreach more effective. Tailor your emails to reflect:

  • Industry Knowledge: Show that you understand their business challenges.
  • Role-Specific Needs: Address issues relevant to their position or responsibilities.
  • Company Context: Mention recent achievements or initiatives specific to their organization.

When to Send Cold Emails


Best Times to Send

The timing of your cold emails can greatly influence response rates. Here are some ideal time frames to consider:

  • Tuesday to Thursday tends to see better open rates.
  • 10:00–11:00 AM is a high-engagement period.
  • 2:00–3:00 PM also performs well for engagement.

On the flip side, avoid sending emails during these times:

  • Before 8:00 AM
  • 11:30 AM–1:00 PM (lunch hours)
  • After 4:00 PM
  • Weekends, unless targeting weekend workers.

Managing Time Zones

Timing matters even more when dealing with recipients in different time zones. Here's a quick guide:

Region

Best Send Window (Local Time)

Tips for Success

East Coast (EST)

9:30 AM – 11:00 AM

Send early to stay ahead of West Coast activity.

West Coast (PST)

10:00 AM – 12:00 PM

Factor in the 3-hour difference with EST.

Europe (CET)

10:00 AM – 11:30 AM

Use the overlap with U.S. morning hours.

Asia-Pacific

9:00 AM – 10:30 AM

Consider next-day delivery for better timing.

Leverage tools like Artemis Leads to automate time zone adjustments and ensure your emails hit inboxes at the right moment. Once you've nailed the timing, align your follow-up schedule to keep the conversation moving.


Follow-up Timing Guidelines

Persistence is key, but it’s important to strike the right balance:

  • First Follow-up: Send 3 business days after the initial email.
  • Second Follow-up: Wait 5 business days after the first follow-up.
  • Third Follow-up: Send 7 business days after the second follow-up.
  • Final Attempt: Follow up 10 business days after the third attempt.

For executive-level contacts, consider extending these intervals by 2–3 days.

Additional tips for refining your follow-up strategy:

  • Speed up follow-ups if the recipient opens your email multiple times.
  • Adjust timing during busy periods specific to their industry.
  • Reset the follow-up schedule if the recipient is out of office or has just returned.

Building Your Email Sequence


Writing the First Email

Your first email should be short, engaging, and immediately useful. Here's how to structure it:

  • Subject line: Keep it brief, relevant, and focused on a key challenge.
  • Opening: Mention a specific detail about the recipient's company or role to show you've done your homework.
  • Call to action: Suggest a clear, low-pressure next step.

Here’s an example structure:

  • Personalization: Show you’ve researched them.: "I noticed your recent expansion into the European market."
  • Problem statement: Highlight a challenge they might face.: "Managing international lead generation can be challenging."
  • Value proposition: Explain how you can help.: "We help B2B companies tackle lead generation issues effectively."
  • Social proof: Share a quick success story.: "Our clients have seen significant improvements in meeting rates."
  • Call to action: Make it easy for them to respond.: "Would you be available for a 15-minute call next Tuesday?"

Once you’ve sent this email, build on it with well-timed, value-packed follow-ups.


Creating Follow-up Messages

Follow-ups should add depth to your initial outreach. Here’s how to approach them:

  • First follow-up: Share a relevant case study or industry insight that ties back to your first email. This helps reinforce your message and adds context.
  • Second follow-up: Address potential concerns by showcasing success stories. If it makes sense, suggest alternative ways to connect, such as LinkedIn. For example, Artemis Leads combines email and LinkedIn outreach to create more genuine conversations.
  • Third follow-up: Offer additional resources or insights to show you’re committed to helping them, even if they haven’t responded yet.

Writing the Final Email

Your last email should strike a balance between professionalism and urgency. Here's what to include:

  • Acknowledge the lack of response in a neutral, respectful tone.
  • Briefly summarize your value proposition.
  • Leave the door open for future contact.
  • Add a clear, time-sensitive call to action.

For instance:

"I understand the timing might not be ideal right now. We’ve helped companies significantly improve their lead generation through personalized multichannel outreach. Feel free to reconnect with us when it’s convenient at [contact information]."


Track and Improve Your Results


Email Performance Metrics

To fine-tune your cold email strategy, keep an eye on these key metrics:

  • Open Rate: Aim for 15-25%
  • Reply Rate: Shoot for 5-15%
  • Meeting Conversion Rate: Strive for 20-30%
  • Bounce Rate: Keep it below 5%
  • Unsubscribe Rate: Stay under 1%

Here's a breakdown of benchmarks for each stage of your email sequence:

Email Stage

Benchmark Metrics

First Email

Opens: 20-30% Replies: 8-12%

Follow-up 1

Opens: 15-25% Replies: 5-8%

Follow-up 2

Opens: 12-20% Replies: 3-6%

Final Email

Opens: 10-15% Replies: 2-4%

Once you've established these benchmarks, test and adjust your approach to improve results.


Testing Different Approaches

Refining your email strategy requires testing different elements systematically. Here's how:

Subject Line Testing

  • Focus on testing one variable at a time.
  • Ensure each variant is sent to at least 200 recipients.
  • Run tests over a full business week.
  • Measure both open and reply rates.

Email Body Testing

  • Experiment with content length, personalization, and call-to-action styles.
  • Test different value propositions to see which resonates most.
  • Analyze response trends to identify effective elements.

Timing Testing

  • Try sending emails on different weekdays.
  • Test morning versus afternoon sends.
  • Adjust follow-up intervals to find the sweet spot.
  • Factor in time zones to optimize delivery times.

Email Management Tools

After testing and refining your approach, use email management tools to streamline and monitor your campaigns. Look for tools with these features:

  • Automated scheduling
  • Open and click tracking
  • Reply detection
  • A/B testing capabilities
  • Comprehensive analytics dashboard
  • Time zone adjustments
  • Bounce tracking
  • Unsubscribe management

These tools can save time and help you stay on top of your email performance metrics.


Summary and Quick Tips

Here’s a quick rundown of tips to sharpen your cold email cadence and improve results:

Get Your Timing Right

  • Send emails between Tuesday and Thursday, ideally from 10:00 AM to 2:00 PM in your recipient's local time.
  • Stick to consistent follow-up intervals.
  • Plan for a sequence that spans 2-3 weeks.
  • Pause your campaigns during major holidays to avoid low engagement.

Refine Your Email Sequence

  • Limit initial emails to fewer than 150 words.
  • Include a clear and specific call-to-action.
  • Personalize opening lines with insights tailored to the recipient's company.
  • Keep follow-up emails concise and focused.
  • Wrap up the sequence with a break-up email to close the loop.

Here’s an example of an effective email sequence:

Day

Action

Key Focus

Day 1

Initial Email

Highlight value proposition

Day 4

Follow-up # 1

Provide additional context

Day 8

Follow-up # 2

Share a case study or social proof

Day 14

Final (Break-up) Email

Offer a last chance to engage

Fine-Tune Your Strategy

  • Track open rates and adjust email timing based on performance.
  • Experiment with different subject lines to see what resonates.
  • Analyze reply rates at each step in the sequence.
  • Keep a record of what works best for different industries or target groups.

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